The artichoke is one of the oldest cultivated plants in the world and has been used in traditional medicine as a specific liver and gallbladder remedy.  The leaves of the artichoke have a high content of pharmacologically relevant
ingredients, with the three essential groups being the caffeeoylquinic acids (CCS), flavonoids and bitter substances. Extensive research shows that the caffeeoylquinic acid group is the active component of the artichoke leave extract
that promotes choleresis (secretion of bile by the liver into the gallbladder), stimulates liver cell function and the production of bile

Cardunara is effective as a natural aid to lower cholesterol and for cases that fall within the framework of functional dyspepsia (pain in the upper abdomen, indigestion, bloating, fullness, belching, heartburn, nausea, GERD, and gastritis). The increase of bile production and flow is advantageous for the digestion of fats, detoxification of the liver/gallbladder system, stimulation of intestinal peristalsis, protection of the intestinal mucosa and results in overall better digestion. Due to the effects on fat metabolism, excessive cholesterol and triglyceride values in the blood are lowered. It promotes better blood flow through the liver and stimulates liver regeneration.

What does artichoke have to do with cholesterol? The origin of cholesterol blockers began in the 1950s after the discovery of the active ingredients found in artichoke leaves. Pharmaceutical cholesterol blockers, such as Lipitor, are derived from synthetic extract of artichoke leaves. Cardunara is a safe and natural alternative of artichoke leave extract that can be used for cholesterol lowering, without side effects. The artichokes that Nestmann Pharma uses in Cardunara are grown under controlled conditions in Northern Bavaria, with no pesticides or artificial fertilizers. These artichokes have particularly high contents of the active ingredients (caffeeoylquinic acids and flavonoids), and are processed and standardized within three days of being harvested to preserve the medicinal properties.